Read e-book online DNA Methylation Microarrays: Experimental Design and PDF

By Sun-Chong Wang,Art Petronis

ISBN-10: 1420067273

ISBN-13: 9781420067279

offering an interface among dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental layout and Statistical Analysis provides the statistical equipment and instruments to research high-throughput epigenomic info, specifically, DNA methylation microarray info. considering those microarrays percentage an identical underlying ideas as gene expression microarrays, a number of the analyses within the textual content additionally practice to microarray-based gene expression and histone amendment (ChIP-on-chip) reviews.

After introducing uncomplicated statistics, the e-book describes wet-bench applied sciences that produce the information for research and explains the best way to preprocess the knowledge to take away systematic artifacts because of size imperfections. It then explores differential methylation and genomic tiling arrays. targeting exploratory info research, the subsequent numerous chapters express how cluster and community analyses can hyperlink the features and roles of unannotated DNA components with identified ones. The e-book concludes by way of surveying the open resource software program (R and Bioconductor), public databases, and different on-line assets on hand for microarray learn.

Requiring simply restricted wisdom of information and programming, this publication is helping readers achieve an outstanding figuring out of the methodological foundations of DNA microarray analysis.

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Read Online or Download DNA Methylation Microarrays: Experimental Design and Statistical Analysis (Chapman & Hall/CRC Biostatistics Series) PDF

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DNA Methylation Microarrays: Experimental Design and Statistical Analysis (Chapman & Hall/CRC Biostatistics Series) by Sun-Chong Wang,Art Petronis

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